diff --git a/lib/runtime-c-api/build.rs b/lib/runtime-c-api/build.rs
index bc8ad1af6..f78c5cf69 100644
--- a/lib/runtime-c-api/build.rs
+++ b/lib/runtime-c-api/build.rs
@@ -19,6 +19,7 @@ fn build() {
     cbindgen::Builder::new()
         .with_crate(crate_dir.clone())
         .with_language(Language::C)
+        .with_include_guard("WASMER_H")
         .generate()
         .expect("Unable to generate C bindings")
         .write_to_file("wasmer.h");
@@ -26,6 +27,7 @@ fn build() {
     cbindgen::Builder::new()
         .with_crate(crate_dir)
         .with_language(Language::Cxx)
+        .with_include_guard("WASMER_H")
         .generate()
         .expect("Unable to generate C++ bindings")
         .write_to_file("wasmer.hh");
diff --git a/lib/runtime-c-api/wasmer.h b/lib/runtime-c-api/wasmer.h
index 4df5001ef..0cfd919c9 100644
--- a/lib/runtime-c-api/wasmer.h
+++ b/lib/runtime-c-api/wasmer.h
@@ -1,3 +1,6 @@
+#ifndef WASMER_H
+#define WASMER_H
+
 #include <stdarg.h>
 #include <stdbool.h>
 #include <stdint.h>
@@ -127,3 +130,5 @@ uint32_t wasmer_table_length(wasmer_table_t *table);
 wasmer_table_result_t wasmer_table_new(wasmer_table_t **table, wasmer_limits_t limits);
 
 bool wasmer_validate(uint8_t *wasm_bytes, uint32_t wasm_bytes_len);
+
+#endif /* WASMER_H */
diff --git a/lib/runtime-c-api/wasmer.hh b/lib/runtime-c-api/wasmer.hh
index 5fb292cb1..1d2c7d0af 100644
--- a/lib/runtime-c-api/wasmer.hh
+++ b/lib/runtime-c-api/wasmer.hh
@@ -1,3 +1,6 @@
+#ifndef WASMER_H
+#define WASMER_H
+
 #include <cstdarg>
 #include <cstdint>
 #include <cstdlib>
@@ -129,3 +132,5 @@ wasmer_table_result_t wasmer_table_new(wasmer_table_t **table, wasmer_limits_t l
 bool wasmer_validate(uint8_t *wasm_bytes, uint32_t wasm_bytes_len);
 
 } // extern "C"
+
+#endif // WASMER_H